Title：The Supportive Role of Tumor Microenvironment in Medulloblastoma Tumorigenesis

Speaker：Zeng-jie Yang, M.D., Ph.D.

        Assistant Professor

        Cancer Biology Program

        Fox Chase Cancer Center

时  间： 2014年11月12日上午10:00

地  点：D122会议室

代表性论文：

1. Li, P., Du, F., Yuelling, L.W., Lin, T., Muradimova, R., Tricarico, R., Wang, J., Enikolopov, G., Bellacosa, A., Wechsler-Reya, R.J., Yang, Z.J. A population of Nestin expressing progenitors in the cerebellum exhibits increased tumorigenicity.Nature Neuroscience 16: 1737-1744, 2013.

2. Yang, Z.J., Ellis, T., Markant, S.L., Read, T.A., Kessler, J.D., Bourboulas, M., Schüller, U., Machold, R.,Fishell, G., Rowitch, D.H., Wainwright, B.J., Wechsler-Reya, R.J. Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells. Cancer Cell 14:135-145, 2008.

3. Yang, Z.J., Wechsler-Reya, R.J. Hit ‘em where they live: Targeting the cancer stem cell niche. Cancer Cell 11:3-5, 2007.

4. Yang, Z.J., Appleby, V., Coyle, B. Chan, W.I., Tahmaseb, M., Wigmore, P.M., Scotting, P.J. Novel strategy to study gene expression and function in developing cerebellar granule cells. J. Neurosci. Methods 132:149-160, 2004.

5. Yuelling, L.W., Du, F., Li, P., Muradimova, R., Yang, Z.J. Isolation of distinct cell populations from the developing cerebellum by microdissection. Journal of visualized experiments: JoVE, doi:10.3791/51323 (2014).

联系人：周光飚，联系电话：6480 7951

欢迎参加！